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Newbie looking to meet others with MFI

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  1. #1
    megtheteacher
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    Newbie looking to meet others with MFI

    Hi everyone,

    After TTC for almost a year, we recently went to have tests. It looks like I am ok, but dh's SA came out with under a million - only 260,000 healthy boys. No idea at this stage why, though he does have two kids from a previous r'ship, so we're hoping it might come good.

    First appointment with specialist at fertility clinic this friday. What should I expect?

    This is a great site, guys. I looking forward to meeting you all.

    Meg x


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  3. #2
    abby26
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    Hi, I am in the same boat. My DH has even less sperm, and he also has an 8 yr old. After seeing urology and endocrinology, we moved on to the fertility doc. Long story short, he had to get a testicular biopsy to get the sperm out for ivf. It has failed twice, but the good news is the sperm did fertilize the eggs, and we had above average embryos. We have more sperm frozen. If I were you, I would go ahead and familiarize yourself with the ivf process, if his count doesn't change it's too low for iui. They will probably check to make sure it's not a hormonal issue. My DH also had an ultrasound. We still don't know WHY. On an emotional level, be prepared for some resentment about him fathering children previously. (unless you are a better person than I am ) and him feeling horrible and guilty. Let me know if I can help you, I know what you're going through!!
    abby


  4. #3
    megtheteacher
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    Hi Abby,

    I'm sorry to hear about the IVFs. I hope your future attempts turn out better for you both.

    Yeah - IVF/ICSI is really our best bet at the moment, unless they can work out what the problem is and get it treated. I've figured out some of the problems it "could" be (I think I've spent too many hours on the internet researching this!) My "best case scenario" is a zinc/iron deficiency, as dh is a vegetarian. Its not varioceles and there's no lumps in places there shouldn't be. But we'll see. I imagine we'll get the tests out of the way in the next couple of weeks, and there's really no point speculating. As you say, there might not even be a reason that they can find.

    Yes... the resentment thing - I'm trying not to let it get the better of me, but its not always easy, especially since the kids were both "accidents". It's just hideously unfair really.

    Thanks for your advice. I'll let you know how it goes

    Meg x


  5. #4
    mmi
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    Go to a clinic that truly has good statitics for IVF/ICSI. You can go to the CDC site and research assisted reproduction and then click on your state. Even with our IVF's with "great looking embryo's" they all failed. We RELUCTANTLY had to go donor sperm.... but now that we are a family, just wish we wouldhave gone that route much quicker(and before we spent over $30,000 out of pocket). best of luck.
    3 years and 15 medicated cycles(clomid, injections, iui's, ivf's, fet, you name it) and 2 angels before finally getting princess 1 (1999)

    2 injection cycles for princess 2(2002)
    Truly miracles!

    "Life isn't measured by the number of breaths we take, but by the moments that take our breath away."


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    Julie4
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    Hi mmi-
    I read your post and wanted to follow up with you. I'm wondering what your MF situation was and how many IVF/ICSI cycles you went through before moving on to DS? My DH has oligoasthenozoospermia and we have failed 3 IVF/ICSIs so far and are thinking of moving on to DS. The embryologist told us that even though the sperm issue is our only identified problem and our emryos have all looked great, the research is now showing that the sperm of males with this condition is often not capable of further chromosome division, so even the great looking embryos arrest after transfer and thus fail to implant. Have you heard of this? Maybe your situation was different? Thanks, Julie


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    abby26
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    Hey, everybody. I too am worried about the sperm not continuing to divide, but my RE has never mentioned it. However, this story might give you some hope. A woman I work with, her DH's testes stopped growing as a child. They had to do TESE on the day of retrieval b/c they said the sperm, if there even were any, would be too fragile to be frozen. They got 10, not even enough for all her eggs, and it worked the first time. So it does happen, just not for us yet!!


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    megtheteacher
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    Hi girls, thanks for your feedback. So, the SA we got was bsically just low in number - morphology and motility were both ok. Would that impact our chances for IVF/ICSI in a positive way, do you think?

    mmi - thank you for your help. i am in Australia though, so the system is a little different. There's only a few major clinics here. You don't really get that much of an opportunity to take your pick, as it's funded by the public system.


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    hope28
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    For Julie

    Hi Julie,
    MY Dh has azoospermia-no sperm is ejaculate because of blockages. We have to use TESE (testicular) sperm. I have done 3 IVF's all failures with excellent quality embryos. My RE said that same exact thing about they must fail to divide at a certain point and do not implant. This last time I transferred 5 pre-blasts, no fragmentation, still no pregnancy. Did your Re explain why this happens? I just don't understand why this works for some people and others it don't. I just don't get it. My Re thinks we should opt for donor sperm too.
    I would love to chat with you about your experiences. Kris
    Kris (35) DH (39) dx: male factor
    IVF #3 and #4 successful.


  10. #9
    Julie4
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    Hi Kris,
    Our embyologist explained to us that the sperm in males with MF are not maturing correctly likely b/c of a microdeletion on the Y chromosome that codes for sperm production, or from blockages also. So, the sperm are able to fertilize eggs initially, but after a certain phase in cell division (meiosis), the chromosomes on the sperm are no longer able to divide themselves correctly and what results is something called embryos with "complex abnormalities". Meaning that when male factor is the issue then the embryos often have two or more chromosomal abnormalities and do not implant and this is true even when the embryos look great on day 3 or 5. The only way to know if any of the embryos are normal is to do PGD on them and that is really expensive and has a few risks involved. The embryologist also said that when the eggs are the issue (versus the sperm) that embryos often have one chromosomal abnormality, so they are more likely to implant and then either miscarry or survive (i.e., like in Down's syndrome).

    Our clinic is now pushing us to do DS too, since we have had 3 failures, all with great looking embryos. Have you and you DH decided what your next step will be? Also, feel free to send me a private message if you prefer. Hope this info helps. Julie


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    mmi
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    We did multiple clomid cycles with IUI, a couple superovulation with injections and IUI and 2 fresh and 1 frozen IVF before moving to donor sperm. My dh actually had counts of 15-20 million with great motility, poor morphology of 6%. They really thought we would get pregnant with just IUI. Like I said before, I really think some sperm issues can't just be fixed with ICSI.

    Going to donor was a very hard decision, but I can tell you, once that miracle is in your arms, you know it is the one God meant for you to have. My dh was the one who decided for baby 2... and I said, lets go to NYC or a big clinic somewhere and try IVF again. His response... "no way, I could never love any baby more than my daughter, we are not going thru that pain, money and stress again, we are doing donor end of discussion"...... Now they are almost 4 and 6, we are not telling them or anyone about the donor stuff.... and to be honest, we rarely even think about it. We are a family, I am mom, he is dad... our kids are loved, happy, healthy and we all feel very blessed.

    feel free to pm me anytime ...... Hugs....
    3 years and 15 medicated cycles(clomid, injections, iui's, ivf's, fet, you name it) and 2 angels before finally getting princess 1 (1999)

    2 injection cycles for princess 2(2002)
    Truly miracles!

    "Life isn't measured by the number of breaths we take, but by the moments that take our breath away."


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