clomid to treat recurrent miscarriage?

[ujkcih]

I have just experienced my 7th miscarriage (first trimester) in the past several years. I have had siccessful pregnancies previously, but now that I am 41, I am experiencing secondary infertility.

My doctor suggested yesterday that we consider trying clomid to treat the recurrent pregnancy loss. He said it could improve egg quality, as well as treat any luteal phase defect.

I can't seem to find any research on the use of clomid to treat recurrent miscarriage in women over 40 (or in anyone, actually). Do any of you have any info on this subject? All feedback welcome.

Thanks!

[Tia38]

I am very sorry for your losses. Have you had testing for recurrent m/c? Usually after 3 or more m/c they will run a battery of tests.

I have not heard of Clomid to treat recurrent m/c. I have also not heard of it improving egg quality or helping with luteal phase defect. But I am not a doc.

I believe progesterone support helps with LP defect.

I have heard of Clomid thinning linings, especially for those 35+. In fact, some believe Clomid is not recommended for 35+ (but it's a bit of a religious war).

My RE recommended three tries of a tx before moving on. At 38 I didn't want to waste time on Clomid. My first Clomid+IUI was a BFP but subsequent m/c. When they let me cycle again I was non-responsive to the Clomid. Rather than try the third time (and/or increase the dose), at 39 I asked to move onto injectables. I have seen some 40+ success stories on Clomid. For me, injectable IUI did the trick (at 39, and now again at 41).

If you go the Clomid route to start I wouldn't do it for more than 3 cycles. Read up a bit on Clomid for 35+. Ask about progesterone support for LP issue.

I would also ask what other testing is available for recurrent pg loss. This is not something I had experience with, but I recall there being some simple meds and protocols that can help.

Best of luck,
-Tia