High FSH and LH, Azoospermia

[Vip]

I would be thankful to you for your valuable sugestion: My Tests report is as follows:
I am 32 Years male with normal sexual features and normal sex life, I was seriously ill when I was 25 Yrs. old doctor diagnosed falariasis, typhoid, my scortum got swelling and then it subsided and dead skin of scortum pealed off slowly then every thing became normal , Earlier when I was 12 Yrs. I got Mumps.
At the age of 32 I discovered that I am Azoospermic, doctor took few tests:
emen analysis:Volume-3ML,apeearence-whitish fluid,sperm count-Zero,WBC-3 to 5 per field,epithilial cells-few.
Blood: Sugar fasting 73,PP 85.
VDRL: non reactive
FSH:43.25, LH: 37.55
Scrotum ultrasound:B/L reduced terticular volume and reflectivity with epididymal fibrosis and patchy calcification of the tunica.( Rt.measure3.3X1.5X1.4 cm & Left measure2.8X1.3X1.2 cm in diameter.
Then he gave Testestrone injections(Weekly) for 2 months and afterwards Profasi 2000(hCG) twice a week for two months.
I Want to know that is There any possibility for me to father a child? What can be the future course of treatment?
Thanks & Regards

[zon]

VIP
I'm sorry to hear that you have to deal with azoo. My dh has azoo due to klinefelter's his FSH and LH levels are also elevated but that is normal in NOA. However, I'm very surprised that your dr put you on testestorone shots for two months as artificial testosterone injections can make you sterile. Urologist that specializes in MF would not do that, they would put you on Clomid ( most popular) or other injecions that will make your body to produce the testosterone on it's own. With aftificial testosterone, the body is getting a signal that the testosterone levels are fine ( thinking that it's producing enough test ) where in fact it stops producing testosterone and stoping sperm production.
Also, mumps could have effect on the fertility as well. You need to find a good dr that will be able to run more tests, etc. I don't know where you are, but check out Cornell website and you can email Dr Schlegel at Cornell ( best in the country ) with all your questions, and he'll be able to give you an idea what to do next.

there is a possibilty that you still produce sperm but they just don't get out. If it;s a obstructive azoospermia than it could probably be fixed, if it's non-obstructive azoo than you can go under the prodedure called microdicession TESE to find sperm and do IVF/ICSI ( where they insert the sperm inside the egg, so even non motile sperm will be fine) My dh and I did TESE/IVF/ICSI in March and were lucky to find some sperm but our two embies didn't stick. Dr. Schlegel did the procedure and he is the best in MF
I hope this answers some of you questions,
And I think you should try to email DR S and see what he might suggest
Best of luck to you

[Vip]

hCG can start spermogenecis, as it is only way to start testicular atrophy treatment .I need some advice on this and how long it will take to restore fertility?

[zon]

hCG on its own can stimulate testosterone production, but not sperm production. On its own it can also cause an increase in testicular size and sensitivity as they start to produce their own natural testosterone.

For sperm production, if fertility is required hMG is required or hCG in combination with a FSH medication.

It can take anything from 6 to 18 months for sperm production to commence. There is little indication on how well this type of treatment will work, it might take 12 months to produce any affect and then go suddenly to normal sperm production so natural conception is possible.

If a low level of sperm production is achieved it might not be possible to achieve natural conception but enough sperm could be produced so a form of IVF or other assisted fertilisation programme can be attempted.

[because]

I would be thankful to you for your valuable sugestion: My Tests report is as follows:
I am 32 Years male with normal sexual features and normal sex life, I was seriously ill when I was 25 Yrs. old doctor diagnosed falariasis, typhoid, my scortum got swelling and then it subsided and dead skin of scortum pealed off slowly then every thing became normal , Earlier when I was 12 Yrs. I got Mumps.
At the age of 32 I discovered that I am Azoospermic, doctor took few tests:
emen analysis:Volume-3ML,apeearence-whitish fluid,sperm count-Zero,WBC-3 to 5 per field,epithilial cells-few.
Blood: Sugar fasting 73,PP 85.
VDRL: non reactive
FSH:43.25, LH: 37.55
Scrotum ultrasound:B/L reduced terticular volume and reflectivity with epididymal fibrosis and patchy calcification of the tunica.( Rt.measure3.3X1.5X1.4 cm & Left measure2.8X1.3X1.2 cm in diameter.
Then he gave Testestrone injections(Weekly) for 2 months and afterwards Profasi 2000(hCG) twice a week for two months.
I Want to know that is There any possibility for me to father a child? What can be the future course of treatment?
Thanks & Regards

hello. Husband has azoo. We were able to find sperm cells sufficient(according to lab reports) to be used with IVF treatment. This was done from a testicluar biopsy. He also has normal function. There were no sperm at all in the samples he gave even after a surgery. It is our thinking that this condition was caused by virus. But no dr's can or will say. ( we have a 10yr old daughter) So something happened along the way. We plan to persue IVF with TESA. There is hope for you if you can find sprem difectly from the testes.

[Vip]

Dear Zon, your sugestion is very valuable but 6 to 18 months there is no reliability to become fully fertile, but this is the only way to see whether this works or not? Thanks

[Vip]

My testes size has increased, what can be the possible ways to get normal sperm counts?

[Vip]

Nobody bothers to give sugestions???