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IVF & High Tech This board is for people going through, or seeking information on InVitro Fertilization and other high tech treatment. Please feel free to post your questions, provide information and interact with other members.

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Old 02-25-2007, 02:43 PM   #1 (permalink)
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Join Date: Feb 2006
Location: Toronto
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Anyone do an antagon cycle then do better on long lupron?

My first IVF was an antagon cycle. I pushed for this cycle and RE agreed because I always produced 1 egg during my IUI's, therefore, we both thought I would be a poor responder, in the sense that I wouldn't produce lots of eggs. After this cancelled IVF, we both agree that I'm not necessarly a poor responder meaning, few eggs, but more so that I always have a dominant follicle. This IVF showed 11 follicles - one was dominant.

I realize most people do long lupron or a variation first. Has anyone done an antagon cycle with no success and then done better on long lupron.

Thanks!!!

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Old 02-25-2007, 06:42 PM   #2 (permalink)
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Hello - yup, my DP had a much better cycle on lupron than on cetrotide. We had done the cetrotide protocol, not because we thought she was a poor responder but due to timing (our RE cycles women in groups and due to work/school timing we wanted to be a part of a certain group so the cetrotide protocol worked best). Here were our results:

Cetrotide protocol:
20+ follicles
12 eggs (some follies contained blood - DP has endometriosis)
6 mature eggs
5 fertilized
transfered 3 on day 3; none to freeze
result: chemical pg

Lupron protocol:
>25 follies
27 eggs!!!
20 mature
17 fertilized
10 made it to blasts!!! Transfered 3 (2 into me and 1 into DP), froze 7!!!
result: me: BFN DP: pg but m/c (blighted ovum)

We still have our 7 frozen - so we're still on this journey, but the lupron protocol definitely was better for us. I remember someone else who also responded much better on lupron after a antagon (same as cetrotide) protocol.
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Me 31, DP 34 TTC for 3 1/2 years
Dx: Me - anovulatory cycles, PAI-1 mutation DP - stage 3 endo, MTHFR mutation
Tx: Combined: >16 IUIs, IVF x3 (4 fresh transfers), FETx1, Losses - m/c x2, chemical pg x2.
Me: Hudson born 11/3/07
DP: IVF #3 BFP - (delivered at 34 weeks) Bennett & Kate 3/28/08
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