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Old 02-24-2005, 10:35 AM   #1 (permalink)
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ShellyN Level 1
Question Severe MF - Need Advice (pg, m/c ment)

Hi all,

Some of you may remember me from my posts last sept-oct. Since then, I have been lurking, reading posts and praying for all the cyclers here on FT.

My bkgnd - We did our first IVF with TESE/ICSI/PGD in sept due to Dh's diagnosis of non-obstructive azoospermia. During the TESE, the RE identified DH's condition as "Sertoli-Cell only", but found some swimmers (altho not mature) to use. I got a BFP, saw a beautiful HB but then m/c at 10 wks. Actually, the embie had arrested around 7 wks but we found out only at 10 wks when I had my u/s.

Incidentally, they had recovered 27 eggs, all of them fertilized but only 10 made it to the PGD on day 3. The PGD revealed 8 abnormal due to bad sperm quality. Of the 2 normal ones, 1 arrested before our 5th day t/f so I had only 1 transferred.

The reason I am writing all these details, is 'cos I need advice on whether it is worth trying all this again?? I had a very difficult time getting over the m/c and had decided that I cudn't live thru all the upheavels again. But as time goes by, I wonder if I will regret this decision later. I know IVF is a numbers game. But the numbers from my cyle have been quite dismal.

My question - Has anyone heard of a "sertoli cell-only" condition make good viable embies? Given that of the 27 eggs, not even 1 embie was viable, is it reasonable for me to hold out hope and commit to another cycle?

Your thoughts please...

Thank you all for listening (reading)!

Shelly

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Old 02-24-2005, 10:55 AM   #2 (permalink)
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Shelly,

I am not familiar with your DH factor but am familiar with other parts of your post. I too had IVF but in Nov 2004, BFP, lost baby at 8.5 weeks but discovered at 12 weeks. I am still healing emotionally (and physically) from the whole experience. You and your DH need to figure out together what you want to do. It is an awful rollercoaster to be on and I wish none of us had to be on it, but fact is, we are here and doing it. It takes time after loss like yours to heal and be well again especially emotionally. Give yourself that time before making any definate decisions about your future.

Best wishes,
Kara
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Old 02-24-2005, 12:08 PM   #3 (permalink)
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First of all I want to say how sorry I am that you have to go through this. My DH rcv'd this dx back in 2000. I remember all to well what a difficult time that was for us. I can imagine how much more dificult it is for you having a mc on top of the dx.

The only advice that I can offer is that you need to take time to grieve before making a decision. Only you and your DH can decide what the right path is for you. It is a very personal decision.

We spent a few months last year investigating using TESA with a MF Specialist. In the end we decided that ds was still the right path for our family. However, this was our decision. The Dr's were more than willing to go ahead. If there was no chance of having good embies and a successful outcome then I don't believe that the dr's would have been willing to do the procedure.

I wish you the best of luck in what ever path you choose.

s
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Old 02-24-2005, 04:10 PM   #4 (permalink)
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First, I want to tell you how sorry I am for your loss. Your situation is very similar to mine. IVF #1 retrieved 26 mature eggs, feritlized. M/C 7 wks IVF#2 24 mature eggs, transfered 4-nothing. Our issue is severe MF. We decided that we couldn't risk another round of IVF we have decided to move on to DIUI, way cheaper and the donor is proven. It took 2 years to get to this point, I had to let DH "deal". I'm in no way saying this is the right decision for you but just wanted to let you know there are other options.
Good luck with whatever you choose.
Bren
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Me (31) DH (29)
DH-severe MF
2-03 IVF#1 m/c
3-03 IVF#2 BFN

moving on to DIUI
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Old 02-24-2005, 04:15 PM   #5 (permalink)
mmi
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We did three IVF with poor morphology issues. Had a screwy urologist.... (he initially told us that we would get pregnant with no problem). After spending 25, 000 and three years of misery, we very reluctantnly went to donor sperm. We now have 2 beautiful little girls and our family is complete. It was a huge decision and not one made with much enthusiasm to go to donor... but once your miracle is in your arm, you can't imagine any other baby. WE feel 100% complete and only wish we would have gone to donor sooner. good luck with your decision.
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