ANA levels?

CeeNZ · 10-05-2009, 07:48 PM

Hi everyone,

Does anybody know what level of anti-nuclear antibodies (ANAs) is considered "high", in the world of IVF? Mine are at 1:640, which I think is pretty high, but my RE here says elevated levels can be found in healthy people. I just have a gut feeling that this is the cause (or one of the causes) of our implantation failure.

Also, for those of you with high ANAs, what has been your course of treatment? Steroids? IVIg? Itralipid? I live in New Zealand and the most anyone is willing to do on me here is steroids.

Thanks.

rjc0704 · 10-06-2009, 05:43 AM

I have borderline + anti-nuclear antibodies. I will check my lab work for the ranges and let you know. I am taking Dexamethasone vs. presidsone for it. IVIG and Intralipids are typically for NKactivity and high th1/th2 cytokyne ratios, I believe.

chelsharmony · 10-09-2009, 11:25 AM

i have borderline ANA and +APA and i was told that i needed to be rechecked since sometimes they can raise and lower by themselves.
I am taking baby aspirin for the +APA and thought that if i had the +ANA i would need heparin instead but not sure.
Do you know what the steroids do for the ANA? I am taking prednazone at the moment in hopes for a BFP and then running into the doc for IVIg treatment when BFP shows. I have very high natural killer cells and doc said this was a good treatment since i can get preggo, just dont ever stay preggo.
What about you ladies?

Patience · Yesterday, 06:01 PM

a high ANA can be a number of things.. you need to have them test you for APS... sometimes high ana's can come from that which would explain implantation failure

**BC-RyansHope** · Yesterday, 06:48 PM

ANA- I was told anything over 320 is positive. My level in Jan was 2560!
Did a ton of labs and guess what they couldnt find a reason for it.

10-05-2009, 07:48 PM	#1 (permalink)
CeeNZ 0-99 post 2 of hearts Join Date: Apr 2009 Location: New Zealand Posts: 20	ANA levels? Hi everyone, Does anybody know what level of anti-nuclear antibodies (ANAs) is considered "high", in the world of IVF? Mine are at 1:640, which I think is pretty high, but my RE here says elevated levels can be found in healthy people. I just have a gut feeling that this is the cause (or one of the causes) of our implantation failure. Also, for those of you with high ANAs, what has been your course of treatment? Steroids? IVIg? Itralipid? I live in New Zealand and the most anyone is willing to do on me here is steroids. Thanks.

10-06-2009, 05:43 AM	#2 (permalink)
rjc0704 1000-4999 post queen of hearts Join Date: Jan 2008 Location: Madison, CT Posts: 1,036	I have borderline + anti-nuclear antibodies. I will check my lab work for the ranges and let you know. I am taking Dexamethasone vs. presidsone for it. IVIG and Intralipids are typically for NKactivity and high th1/th2 cytokyne ratios, I believe. __________________ Rhonda & DH ttc#1: 5 long years 3 natural preg - all m/c before 8wks 1 IVF - cancelled-poor response 11/06 On to Donor Cycles: 3 DE-IVF - BFN BFN BFN Immunity Issues, IR, hydrosalpinx tube 4 totcyles FET #1 Cycle now IN PROGRESS ET est. Dec 7th

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10-09-2009, 11:25 AM	#3 (permalink)
chelsharmony 0-99 post 2 of hearts Join Date: May 2008 Posts: 12	i have borderline ANA and +APA and i was told that i needed to be rechecked since sometimes they can raise and lower by themselves. I am taking baby aspirin for the +APA and thought that if i had the +ANA i would need heparin instead but not sure. Do you know what the steroids do for the ANA? I am taking prednazone at the moment in hopes for a BFP and then running into the doc for IVIg treatment when BFP shows. I have very high natural killer cells and doc said this was a good treatment since i can get preggo, just dont ever stay preggo. What about you ladies?

Yesterday, 06:01 PM	#4 (permalink)
Patience 1000-4999 post queen of hearts Join Date: Jan 2002 Location: NorthEast, Texas Posts: 2,355 Blog Entries: 4	a high ANA can be a number of things.. you need to have them test you for APS... sometimes high ana's can come from that which would explain implantation failure

Yesterday, 06:48 PM	#5 (permalink)
BC-RyansHope FT Diner ~open 24/7 BYOC*~ Join Date: Oct 2006 Location: Missing my Ryan 11/6/08 Posts: 7,372 Blog Entries: 260	ANA- I was told anything over 320 is positive. My level in Jan was 2560! Did a ton of labs and guess what they couldnt find a reason for it.