Sperm DNA Fragmentation

loc · 03-22-2005, 11:28 AM

We turned out not to be having immune caused implantation failures, but severe sperm dna implantation failures. All that wasted ivig...

You are invited to join http://health.groups.yahoo.com/group/DNAFrag/
Sperm DNA Fragmentation testing is one of the latest breakthroughs in reproductive health, miscarriage, and infertility. This group is for couples who have a diagnosis of high sperm DNA fragmentation, or for those who want to find out if this may be the cause of their IVF failures etc. Typically losses happen around day 8 after conception or in vitro fertilization, due to the fact that the paternal genome is supposed to take over at that point. There is growing evidence that SSRIs in addition to other medications, overheating, smoking, excess drinking, etc. cause severe oxiditive stress for sperm and fragment dna. Several couples here are members of an NIH study on DNA fragmentation.

LynnUS · 03-22-2005, 03:49 PM

Very interesting, I've not heard of this. Sorry you've wasted your time and $$ on IVIg.

The good news is you now have an accurate dx and hopefully you can move forward from here and reach your dream soon.

Wishing you all the best!

Lynn

MashaND · 03-23-2005, 06:47 AM

HI LOc,
Your post sounds promising. I hope there is a tx for it and it will help.
I wonder how did they (doctors or yourself?) came up with it? Is it testable only during IVF procedure. I don't know your story very much but you mentioned IVIg. I wonder why they did noit test for sperm DNA fragmentation in the beginning - and did any of the immune issues surface before?
Good luck
Masha

MashaND · 03-23-2005, 06:56 AM

Hi again,
I did some research. It is in fact very interesting! And, it can be corrected by vitamins and supplements! I hope your case is just due to environmental toxins (they probably gonna add selenium, zinc, Vit E, etc.). My advice also - see a naturopath for that - they specialize in antioxidants and that kind of stuff.
Last question. Where and how you get tested and how much was the test?
My husband might have a similar problem and this is why I am being so noisy. Good luck to you again.
M

03-22-2005, 11:28 AM	#1 (permalink)
loc Registered User Join Date: Jan 2004 Posts: 69	Sperm DNA Fragmentation We turned out not to be having immune caused implantation failures, but severe sperm dna implantation failures. All that wasted ivig... You are invited to join http://health.groups.yahoo.com/group/DNAFrag/ Sperm DNA Fragmentation testing is one of the latest breakthroughs in reproductive health, miscarriage, and infertility. This group is for couples who have a diagnosis of high sperm DNA fragmentation, or for those who want to find out if this may be the cause of their IVF failures etc. Typically losses happen around day 8 after conception or in vitro fertilization, due to the fact that the paternal genome is supposed to take over at that point. There is growing evidence that SSRIs in addition to other medications, overheating, smoking, excess drinking, etc. cause severe oxiditive stress for sperm and fragment dna. Several couples here are members of an NIH study on DNA fragmentation.

03-22-2005, 03:49 PM	#2 (permalink)
LynnUS Registered User Join Date: Jan 2002 Location: Long Grove, IL Posts: 3,445	Very interesting, I've not heard of this. Sorry you've wasted your time and $$ on IVIg. The good news is you now have an accurate dx and hopefully you can move forward from here and reach your dream soon. Wishing you all the best! Lynn __________________ JAK, 7/28/05 MAK, 6/25/01

03-23-2005, 06:47 AM	#3 (permalink)
MashaND Registered User Join Date: Nov 2004 Location: Toronto Posts: 1,063 Blog Entries: 7	HI LOc, Your post sounds promising. I hope there is a tx for it and it will help. I wonder how did they (doctors or yourself?) came up with it? Is it testable only during IVF procedure. I don't know your story very much but you mentioned IVIg. I wonder why they did noit test for sperm DNA fragmentation in the beginning - and did any of the immune issues surface before? Good luck Masha __________________ Me:31 , DH: 35 TTC # 1 since 2001 Dx: Tubal, PCOS, immune & bacterial issues 1 Ectopic angel. to get soon

03-23-2005, 06:56 AM	#4 (permalink)
MashaND Registered User Join Date: Nov 2004 Location: Toronto Posts: 1,063 Blog Entries: 7	Hi again, I did some research. It is in fact very interesting! And, it can be corrected by vitamins and supplements! I hope your case is just due to environmental toxins (they probably gonna add selenium, zinc, Vit E, etc.). My advice also - see a naturopath for that - they specialize in antioxidants and that kind of stuff. Last question. Where and how you get tested and how much was the test? My husband might have a similar problem and this is why I am being so noisy. Good luck to you again. M __________________ Me:31 , DH: 35 TTC # 1 since 2001 Dx: Tubal, PCOS, immune & bacterial issues 1 Ectopic angel. to get soon

Similar Threads
Thread	Thread Starter	Forum	Replies	Last Post
Sperm DNA Fragmentation	hope28	Male Factor	1	04-13-2005 05:15 AM
UK: People donating sperm and eggs will no longer have right to remain anonymous	nathanzmom	Donor Issues (Egg & Sperm)	2	04-05-2005 09:29 AM
Sperm not moving or "dead"???	infertilemertle	General Infertility	2	03-07-2005 02:57 PM
"Laptops might reduce sperm production"	BC-Maura	Male Factor	1	02-25-2005 11:23 PM
1st SA back - low sperm count	sarahp	Male Factor	15	02-19-2005 07:47 AM

Currently Active Chat Room Users: 0 \| Scheduled Chat Room Events
	Users in Chat Rooms: No one's chatting right now!

VISIT OUR SISTER SITES:
JustMommies Pregnancy Calendar	eHarmony Advice Dating Advice	Project Wedding Wedding Songs	Weddingbee Wedding Blog