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  1. #1
    loc
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    Sperm DNA Fragmentation

    We turned out not to be having immune caused implantation failures, but severe sperm dna implantation failures. All that wasted ivig...

    You are invited to join http://health.groups.yahoo.com/group/DNAFrag/
    Sperm DNA Fragmentation testing is one of the latest breakthroughs in reproductive health, miscarriage, and infertility. This group is for couples who have a diagnosis of high sperm DNA fragmentation, or for those who want to find out if this may be the cause of their IVF failures etc. Typically losses happen around day 8 after conception or in vitro fertilization, due to the fact that the paternal genome is supposed to take over at that point. There is growing evidence that SSRIs in addition to other medications, overheating, smoking, excess drinking, etc. cause severe oxiditive stress for sperm and fragment dna. Several couples here are members of an NIH study on DNA fragmentation.


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  3. #2
    LynnUS
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    Very interesting, I've not heard of this. Sorry you've wasted your time and $$ on IVIg.
    The good news is you now have an accurate dx and hopefully you can move forward from here and reach your dream soon.

    Wishing you all the best!

    Lynn
    JAK, 7/28/05
    MAK, 6/25/01


  4. #3
    MashaND
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    HI LOc,
    Your post sounds promising. I hope there is a tx for it and it will help.
    I wonder how did they (doctors or yourself?) came up with it? Is it testable only during IVF procedure. I don't know your story very much but you mentioned IVIg. I wonder why they did noit test for sperm DNA fragmentation in the beginning - and did any of the immune issues surface before?
    Good luck
    Masha
    Me:31 , DH: 35
    TTC # 1 since 2001
    Dx: Tubal, PCOS, immune & bacterial issues
    1 Ectopic angel.
    to get soon


  5. #4
    MashaND
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    Hi again,
    I did some research. It is in fact very interesting! And, it can be corrected by vitamins and supplements! I hope your case is just due to environmental toxins (they probably gonna add selenium, zinc, Vit E, etc.). My advice also - see a naturopath for that - they specialize in antioxidants and that kind of stuff.
    Last question. Where and how you get tested and how much was the test?
    My husband might have a similar problem and this is why I am being so noisy. Good luck to you again.
    M
    Me:31 , DH: 35
    TTC # 1 since 2001
    Dx: Tubal, PCOS, immune & bacterial issues
    1 Ectopic angel.
    to get soon


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