Has anyone heard of this as a reason for abnormal embryos?

DrAndrea · 05-09-2009, 05:52 AM

I had 8 of my 9 embryos come back as abnormal (three were trisomies and 5 were complex abnormals). I went for a second opinion from another doctor. This doctor said that he thinks the previous RE triggered me too early and the embryos didn't have time to properly go thru meiosis. Hence, the eggs were immature. When they triggered me, I only had one 18 and one 19. He said they should have waited, but figured they didn't because my estrogen was slightly increased.

Does anyone buy this explanation?

lw962 · 05-12-2009, 09:31 PM

Dr- I was always told that if a follie is immature, it will absolutely not fertilize. Even with icsi. So being that ur follies fertilized, I would suspect that they were mature. So I do not buy ur re's explaination as the embryologist is the 1 that explained this to me. If I were u I would direct any of my follie or embryo quality questions 2 the embryologist as they are educated in this arena.

05-09-2009, 05:52 AM	#1 (permalink)
DrAndrea 0-99 post 2 of hearts Join Date: May 2009 Location: NY Posts: 37	Has anyone heard of this as a reason for abnormal embryos? I had 8 of my 9 embryos come back as abnormal (three were trisomies and 5 were complex abnormals). I went for a second opinion from another doctor. This doctor said that he thinks the previous RE triggered me too early and the embryos didn't have time to properly go thru meiosis. Hence, the eggs were immature. When they triggered me, I only had one 18 and one 19. He said they should have waited, but figured they didn't because my estrogen was slightly increased. Does anyone buy this explanation? __________________ Me: 31 (NK cells, MFTHR defect, blood clotting issues) DH: 38 (translocation on 1 and 16; borderline DNA fragmentation) 7/30/09 BFP on HPT!!!! (transferred 4 expanding blasts) 7/31/09 (7dp5dt) beta is 38!!!! 8/3/09 (10dp5dt) beta is 205!!!

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05-12-2009, 09:31 PM	#2 (permalink)
lw962 1000-4999 post queen of hearts Join Date: Oct 2007 Location: Miami, FL Posts: 3,763	Dr- I was always told that if a follie is immature, it will absolutely not fertilize. Even with icsi. So being that ur follies fertilized, I would suspect that they were mature. So I do not buy ur re's explaination as the embryologist is the 1 that explained this to me. If I were u I would direct any of my follie or embryo quality questions 2 the embryologist as they are educated in this arena.