CD8 follie check - not to great

Danasingle · 02-05-2007, 03:27 PM

Well, $1900. of meds and I will likely only have two mature follicles. Considering I produce one without meds, it doesn't seem that encouraging.

I wonder what role the Letrozole played?

I have only three follicles. Period: 4.4 mm , 7.6 , 8.5 and my lining is only 3.8 mm- so my E. levels are really low - no danger of LH surge.

I'm to continue at 225 iu of Puregon daily and have another scan on Thursday afternoon. I calculate the most they would grow would be to: 11.4, 14.6 and 15.5 - still not mature.

In comparison, three years ago, I did the same dosage of inject. (but with NO letrozole) and on CD9 I had 19, 15, 14 and a few smaller ones--had to trigger that day because high estrogen level was causing my LH to surge.

I know it only takes one to fertilize.....It's my odds of only 1/10 being capable of getting the chromosomes right that is worrysome....

Dana
CD8

maria2 · 02-05-2007, 10:02 PM

Dana-
The numbers all kinda make my eyes boggle because I don't understand them, but I'm sending you thoughts of fortitude just to see the cycle through without judging it, if you can! You just never know, and can't really! Can't know if this would have turned out this way no matter what, can't know if the meds mess up made the follies smaller. (My favorite strategy btw was to try to see through to the duration of my planned treatment, as in thinking ahead to the end of however many cycles I planned to do rather than focusing on each individual cycle - hard to do, but easier than the cycle by cycle rollercoaster!). So take heart! It's all in the hands of the universe. You've got a big cheering section here for those little growing follicles! And the odds? Well, cross that bridge later - early on in a pregnancy now you can have a test done to update those odds, and for many, they change significantly (I think mine @ 37 went from 1/400 to 1/20000 or something). Thinking of you!!
-maria2

Annaandy · 02-06-2007, 07:29 AM

What did the RE say about it? Don't be discourage, I have a hard time following numbers and such, you still have a few more days and anything could happen in a fe days keep the faith

cs1984cs · 02-06-2007, 04:15 PM

I'm not a number person myself; I usually read the nurse... I panic when she does

otherwise...

I hope all goes well. Hang in there.

CS

littlecalista · 02-06-2007, 04:52 PM

Numbers and stats.....if only they really meant something! I was never supposed to get pg with my eggs, ever. I was never supposed to get pg via DIUI. Surely, my 2 lone follies wouldn't do much either? Well, you know the end to that story.

Just *try* to ride out this cycle and see where it takes you. I know it's so hard not having control. We want all these #'s and stats to give us a clue to our final destination, but only time will tell.

We're all here, holding your hand and hoping along with you.

Many

and heaps of +++++++++ thoughts!

DeeMarie · 02-07-2007, 08:17 AM

Hang in there Dana!

We're all here cheering you on. You never know what can happen! Don't give up on this cycle! It only takes one!!

Kylie · 02-10-2007, 02:35 PM

How is it going now? Did your follies and lining decide to have a growth spurt?

.

Danasingle · 02-10-2007, 05:40 PM

Definitely disappointed. My dominant follicle has taken over and is now 21 mm. My next two are only 12 mm and 9 mm. My lining is 10 mm, so that will be fine.

I take another 225 iu of Puregon tonight, then OPK at 10:00 am tomorrow morning. If +++, then I do nothing and have my DIUI MONDAY am.

If the OPK is still negative, (unlikely, but still possible), then I take 10,000 iu HCG shot at MIDNIGHT Sunday and have my DIUI TUESDAY am.

This was the kind RE. I said 'I know 'it ain't over until it's over', but I expressed my disappointment that I have only one mature follicle after all these drugs, when I would have had one even without any. His response was, 'Don't get discouraged yet, the meds may have helped this egg develop better.'

Even if I do not surge tomorrow, I guess there isn't a chance that second smaller follicle will mature, eh?........

Here was my progression at CD8, CD11 and today at CD13, (plus possible more growth from one more day of meds before DIUI)The other couple of follicles slid off the chart.

8, 16, 21 = This will be the ONE.

7, 9, 12 = This one would have to grow 4 mm from tonight's meds Unlikely, eh?

I have not read any studies that say that the risk of chromosome problems is LESS in an egg supported by FSH. The RE was probably just trying to solace me, eh?

Dana Single - 44
ttc #3 - CD13

maria2 · 02-10-2007, 09:58 PM

I think he sounds like my wonderful doctor, who just always said, it only takes one to work! I'm SO glad the universe took pity on you and gave you a NICE RE today after the crap/lack of info you have had to deal with this cycle from Mr Cranky and his team. This RE works hard too, I bet! Keep us posted, Dana. Lots of sticky cheers going out to your big strong follie!
-maria2

rb · 02-10-2007, 10:16 PM

Don't let anything get you down. You are the one, Neo.

02-05-2007, 03:27 PM	#1 (permalink)
Danasingle 5000-9999 post king of hearts Join Date: Jan 2002 Location: Western Canada Posts: 8,324	CD8 follie check - not to great Well, $1900. of meds and I will likely only have two mature follicles. Considering I produce one without meds, it doesn't seem that encouraging. I wonder what role the Letrozole played? I have only three follicles. Period: 4.4 mm , 7.6 , 8.5 and my lining is only 3.8 mm- so my E. levels are really low - no danger of LH surge. I'm to continue at 225 iu of Puregon daily and have another scan on Thursday afternoon. I calculate the most they would grow would be to: 11.4, 14.6 and 15.5 - still not mature. In comparison, three years ago, I did the same dosage of inject. (but with NO letrozole) and on CD9 I had 19, 15, 14 and a few smaller ones--had to trigger that day because high estrogen level was causing my LH to surge. I know it only takes one to fertilize.....It's my odds of only 1/10 being capable of getting the chromosomes right that is worrysome.... Dana CD8 Last edited by Danasingle; 02-05-2007 at 03:29 PM.

02-10-2007, 10:16 PM	#10 (permalink)
rb 200-299 post 4 of hearts Join Date: Oct 2006 Posts: 226	It's all you, Dana Don't let anything get you down. You are the one, Neo. __________________ 100% Mothra Compatible

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02-05-2007, 10:02 PM	#2 (permalink)
maria2 Registered User Join Date: Jan 2002 Location: Oregon Posts: 477	Dana- The numbers all kinda make my eyes boggle because I don't understand them, but I'm sending you thoughts of fortitude just to see the cycle through without judging it, if you can! You just never know, and can't really! Can't know if this would have turned out this way no matter what, can't know if the meds mess up made the follies smaller. (My favorite strategy btw was to try to see through to the duration of my planned treatment, as in thinking ahead to the end of however many cycles I planned to do rather than focusing on each individual cycle - hard to do, but easier than the cycle by cycle rollercoaster!). So take heart! It's all in the hands of the universe. You've got a big cheering section here for those little growing follicles! And the odds? Well, cross that bridge later - early on in a pregnancy now you can have a test done to update those odds, and for many, they change significantly (I think mine @ 37 went from 1/400 to 1/20000 or something). Thinking of you!! -maria2

02-06-2007, 07:29 AM	#3 (permalink)
Annaandy Registered User Join Date: Jul 2006 Location: FL Posts: 368	What did the RE say about it? Don't be discourage, I have a hard time following numbers and such, you still have a few more days and anything could happen in a fe days keep the faith

02-06-2007, 04:15 PM	#4 (permalink)
cs1984cs Registered User Join Date: May 2006 Posts: 2,198	I'm not a number person myself; I usually read the nurse... I panic when she does otherwise... I hope all goes well. Hang in there. CS

02-06-2007, 04:52 PM	#5 (permalink)
littlecalista 5000-9999 post king of hearts Join Date: Jan 2002 Location: My heart is still in Seattle, the rest of me is in FL Posts: 5,002 Blog Entries: 387	Numbers and stats.....if only they really meant something! I was never supposed to get pg with my eggs, ever. I was never supposed to get pg via DIUI. Surely, my 2 lone follies wouldn't do much either? Well, you know the end to that story. Just try to ride out this cycle and see where it takes you. I know it's so hard not having control. We want all these #'s and stats to give us a clue to our final destination, but only time will tell. We're all here, holding your hand and hoping along with you. Many and heaps of +++++++++ thoughts!

02-07-2007, 08:17 AM	#6 (permalink)
DeeMarie Registered User Join Date: Jan 2007 Location: New Jersey Posts: 304	Hang in there Dana! We're all here cheering you on. You never know what can happen! Don't give up on this cycle! It only takes one!!

02-10-2007, 05:40 PM	#8 (permalink)
Danasingle 5000-9999 post king of hearts Join Date: Jan 2002 Location: Western Canada Posts: 8,324	Definitely disappointed. My dominant follicle has taken over and is now 21 mm. My next two are only 12 mm and 9 mm. My lining is 10 mm, so that will be fine. I take another 225 iu of Puregon tonight, then OPK at 10:00 am tomorrow morning. If +++, then I do nothing and have my DIUI MONDAY am. If the OPK is still negative, (unlikely, but still possible), then I take 10,000 iu HCG shot at MIDNIGHT Sunday and have my DIUI TUESDAY am. This was the kind RE. I said 'I know 'it ain't over until it's over', but I expressed my disappointment that I have only one mature follicle after all these drugs, when I would have had one even without any. His response was, 'Don't get discouraged yet, the meds may have helped this egg develop better.' Even if I do not surge tomorrow, I guess there isn't a chance that second smaller follicle will mature, eh?........ Here was my progression at CD8, CD11 and today at CD13, (plus possible more growth from one more day of meds before DIUI)The other couple of follicles slid off the chart. 8, 16, 21 = This will be the ONE. 7, 9, 12 = This one would have to grow 4 mm from tonight's meds Unlikely, eh? I have not read any studies that say that the risk of chromosome problems is LESS in an egg supported by FSH. The RE was probably just trying to solace me, eh? Dana Single - 44 ttc #3 - CD13

02-10-2007, 09:58 PM	#9 (permalink)
maria2 Registered User Join Date: Jan 2002 Location: Oregon Posts: 477	I think he sounds like my wonderful doctor, who just always said, it only takes one to work! I'm SO glad the universe took pity on you and gave you a NICE RE today after the crap/lack of info you have had to deal with this cycle from Mr Cranky and his team. This RE works hard too, I bet! Keep us posted, Dana. Lots of sticky cheers going out to your big strong follie! -maria2