FSH injections and OPKs

Deneice2004 · 07-26-2008, 03:21 PM

Does anyone know if FSH injections, particularly Bravelle, will cause a false positive in an OPK?

I had a negative OPK yesterday and a positive today, but it is so early in my cycle. Usually I ovulate on CD15 and today is CD11.

I took Clomid CD4-8 and Bravelle 75ius CD 9 and 10.

TIA!!!!!

**BC-Maura** · 07-26-2008, 05:54 PM

Hi there! It might be the Clomid causing a false ++ on your OPK. According to the fertilityplus website, it's recommended that you wait 3 days after stopping Clomid before testing with an OPK. Also according to that site, an FSH only injection should not affect the result so if Bravelle is purely FSH, chances are it's not that. But I'm not sure! You could always call the manufacturer of the OPK and ask.

In the meantime, I would keep OPKing and see what happens. I would definitely not asume that this ++ today was the real thing!

Here are blurbs from the fertilityplus website, btw:

"Q: Does Clomid cause problems with OPKs?

A: Clomid (Serophene/clomiphene citrate) can cause a false positive in OPKs if taken too soon after finishing the prescription. According to most of the manufacturers you should wait at least 3 days before using an OPK. If you take Clomid days 3-7 you can begin testing on day 10. If you take it 5-9, you should wait until day 12.

Q: Can I use OPKs if I am taking injectable fertility drugs such as Pergonal, Humegon, Repronex, Gonal-F, Follistim, or Fertinex?

A: This is a tough one to answer. Pergonal, Humegon and Repronex are made from LH+FSH and may contain enough LH to cause a false reading, though the FSH-only meds, Gonal-F, Follistim and Fertinex, should not effect testing.

With any of these drugs, patients should have follicle size monitored by ultrasound and then get an HCG trigger to induce ovulation when the follicles are large enough rather than relying on OPKs. Many patients do not have a natural LH surge while on injectable medications. Some doctors will ask you to use OPKs in addition to ultrasound monitoring, but be weary of one who goes only by OPKs."

(me again

)

GOOD LUCK and keep us posted+++++++++
Maura

07-26-2008, 03:21 PM	#1 (permalink)
Deneice2004 100-199 post 3 of hearts Join Date: Apr 2007 Location: Mississippi Posts: 143	FSH injections and OPKs Does anyone know if FSH injections, particularly Bravelle, will cause a false positive in an OPK? I had a negative OPK yesterday and a positive today, but it is so early in my cycle. Usually I ovulate on CD15 and today is CD11. I took Clomid CD4-8 and Bravelle 75ius CD 9 and 10. TIA!!!!! __________________ TTC #1 since 08/2007 IUI #1 BFN IUI #2 BFN IVF #1 BFP - Miscarried IUI #3 BFP - Miscarried IUI #4 BFN Taking a break for Egg Donation #6 http://www.fertilityfriend.com/home/1ac30a

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07-26-2008, 05:54 PM	#2 (permalink)
BC-Maura Board Coordinator Join Date: Jan 2002 Posts: 13,270	Hi there! It might be the Clomid causing a false ++ on your OPK. According to the fertilityplus website, it's recommended that you wait 3 days after stopping Clomid before testing with an OPK. Also according to that site, an FSH only injection should not affect the result so if Bravelle is purely FSH, chances are it's not that. But I'm not sure! You could always call the manufacturer of the OPK and ask. In the meantime, I would keep OPKing and see what happens. I would definitely not asume that this ++ today was the real thing! Here are blurbs from the fertilityplus website, btw: "Q: Does Clomid cause problems with OPKs? A: Clomid (Serophene/clomiphene citrate) can cause a false positive in OPKs if taken too soon after finishing the prescription. According to most of the manufacturers you should wait at least 3 days before using an OPK. If you take Clomid days 3-7 you can begin testing on day 10. If you take it 5-9, you should wait until day 12. Q: Can I use OPKs if I am taking injectable fertility drugs such as Pergonal, Humegon, Repronex, Gonal-F, Follistim, or Fertinex? A: This is a tough one to answer. Pergonal, Humegon and Repronex are made from LH+FSH and may contain enough LH to cause a false reading, though the FSH-only meds, Gonal-F, Follistim and Fertinex, should not effect testing. With any of these drugs, patients should have follicle size monitored by ultrasound and then get an HCG trigger to induce ovulation when the follicles are large enough rather than relying on OPKs. Many patients do not have a natural LH surge while on injectable medications. Some doctors will ask you to use OPKs in addition to ultrasound monitoring, but be weary of one who goes only by OPKs." (me again ) GOOD LUCK and keep us posted+++++++++ Maura